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Fibrodysplasia Ossificans Progressiva

GeneticACVR1 mutation1692 (earliest case)New mutation
TypeGenetic
CauseACVR1 mutation
First Known1692 (earliest case)
TransmissionNew mutation

About Fibrodysplasia Ossificans Progressiva

Injured muscle and tendon turn into bone, slowly building a second skeleton. Surgery makes it worse by triggering more bone. Only about 1 in 2 million people have it. Misshapen big toes at birth are the diagnostic clue.

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