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Porphyria

GeneticHeme synthesis enzyme defectsAncient (described)Inherited
TypeGenetic
CauseHeme synthesis enzyme defects
First KnownAncient (described)
TransmissionInherited

About Porphyria

Disorders of blood pigment chemistry with dramatic symptoms. Attacks bring severe abdominal pain and confusion. The madness episodes of King George III match the pattern, though the theory is disputed. Skin variants blister in sunlight, perhaps feeding vampire legends.

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